Computational Modeling Study of the Binding of Aging and Non-Aging Inhibitors with Neuropathy Target Esterase
Neuropathy target esterase (NTE) is a serine hydrolase with phospholipase B activity, which is involved in maintaining the homeostasis of phospholipids.It can be inhibited by aging inhibitors such as some organophosphorus (OP) compounds, which Acc leads to delayed neurotoxicity with distal degeneration of axons.However, the detailed binding conform